Nitin Nigam, M.D.

Our hours of operation are Monday through Friday 8:00 am to 5:00 pm

Vitreoretinal Specialist / Ophthalmology

Professional License


North Carolina   2018

Board Certified Ophthalmologist   2017

Dr. Nitin Nigam provides medical and surgical care to patients with vitreoretinal diseases, with a research focus in retinal neurovascular development and disease.

Dr. Nigam special interests include: Vitreoretinal Diseases and Surgery; Epiretinal Membranes; Macular Holes; Macular Degeneration; Retinal Detachment; Proliferative Vitreoretinopathy (PVR); Proliferative Diabetic Retinopathy; Retinal Imaging and Optical Coherence Tomography (OCT); Retinopathy of Prematurity.

Education and Training

2009-2010   Retina fellowship, Flinders Medical Center, Bedford Park, South Australia, Australia

2006-2008   Retina and Uveitis fellowship, Univ. of California San Diego, Shiley Eye Center

2002-2005   M.D. Ophthalmology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India

1996-2001   M.B.B.S., Institute of Medical Sciences, Banaras Hindu University, Varanasi, India

Work Experience

  • Board Certified Ophthalmologist, Surgical-Medical Retina & Uveitis, Aspirus Ironwood  Hospital and Clinics, Ironwood, Michigan, June 2010-Current

  • Fellowship, Vitreo-Retina, Flinders Medical Center, South Australia, Australia, Feb 2009- Feb 2010

  • Fellowship, Retina and Uveitis, Univ of California, San Diego, California, Aug 2006-Dec 2008

  • Observer-ship, Retina and Vitreous, Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD, June 2005

  • Consultant Surgeon, Guru Nanak Hospital, Gurubagh; Heritage Hospital; Varanasi, India. Mar 2005 – Jun 2006

  • Resident Doctor, Dept. of Ophthalmology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.  Mar 2002 – Mar 2005

  • Medical Internship, Department of Medicine, Sir Sunderlal Hospital, Banaras Hindu University, Varanasi, India Jan 2001 - Dec 2001

Clinical Research

  • Spectral OCT for Imaging ERM, Retinal Edema and Vitreomacular Interface

  • OCT-Raster Scanning and Manual Segmentation in Determining Drusen Volume in Age-Related Macular Degeneration

  • Interferon Induced Sarcoid Uveitis with Papillitis and Macular Edema

  • Prognostic Implications of Pigment Epithelial Detachment in Bevacizumab (Avastin) treated eyes with Age-Related

       Macular degeneration and Choroidal Neovascularization

  • The use of Intraoperative ICG dye to assist in epiretinal membrane removal

  • Color versus Gray-Scale display of images on Ultra-high Resolution Spectral OCT

  • Correlation between Spectral OCT and Fundus Auto-florescence at the margins of Geographic Atrophy

  • The role of Abnormal Vitreomacular Adhesion in Age-related Macular Degeneration

Clinical Trials

Principal Investigator, Current

A Two-Year, Randomized, Double-Masked, Multicenter, Three-Arm Study Comparing the Efficacy and Safety of RTH258 versus Aflibercept in Subjects with Neovascular Age-Related Macular Degeneration: Alcon


Principal-Investigator, Back-up Investigator site

A Multi-Center Randomized Study Evaluating Dosing Regimens For Treatment With Intravitreal Ranibizumab Injections In Subjects With Macular Edema Following Retinal Vein Occulsion: Genentech


Sub-Investigator, Randomized, Double Masked, Active Controlled Phase III Study of the Efficacy, Safety, and Tolerability of Repeated Doses of Intravitreal VEGF Trap in Subjects with Neovascular Age-Related Macular Degeneration. Sponsor: Regeneron


Sub-Investigator, A Phase 2 Multicenter, Randomized, Double-Masked, Placebo   Controlled, Dose-Comparison Study of the Treatment of Geographic Atrophy in Subjects with Age-Related Macular Degeneration. Sponsor: Sirion


Sub-Investigator, A Six-Month, Phase 3, Multicenter, Masked, Randomized, Sham-Controlled Trial (with Six Month Open-Label Extension) to Assess the Safety and Efficacy of 700µ and 350µ Dexamethasone Posterior Segment Drug Delivery System (DEX PS DDS) in the Treatment of Patients with Macular Edema following Central Retinal Vein Occlusion or Branch Retinal Vein Occlusion. Sponsor: Allergan


Sub-Investigator, A 3-Year, Phase 3, Multicenter, Masked, Randomized, Sham-Controlled Trial to Assess the Safety and Efficacy of 700µ and 350µ Dexamethasone Posterior Segment Delivery System (DEX PS DDS) in the Treatment of Patients with Diabetic Macular Edema. Sponsor: Allergan


Sub-Investigator, MUST- Fluocinolone Implant vs. Standard of Care (Oral Corticosteroids, immunosupressives) for the treatment of Uveitis


Sub-Investigator, LSOCA-Longitudinal study of the Ocular Complications of AIDS


Sub-Investigator, Investigator Initiated Grants, HAART- Highly Active AntiRetroviral    (anti-HIV) Therapy


Sub-Investigator: Macular Hole Prospective Survey, Australia


Sub-Investigator: Retinal Vein Occlusion study, Australia


Organizations and memberships

  • American Society of Retina Specialist

  • American Academy of Ophthalmology

  • Association for Research in Vision and Ophthalmology

  • All India Ophthalmological Society

Charitable Activities 

  •  Screening of school children for various ophthalmic ailments in and around Varanasi.

  • Took part in the pulse polio program, carried out by the government of India for eradication of Polio from the country.


Extracurricular Activities 

  • Instrument Rated Private Pilot with 700 hours in single engine high performance plane

  • Advanced Scuba diver